Axonal transcription factors signal retrogradely in lesioned peripheral nerve
نویسندگان
چکیده
منابع مشابه
Axonal transcription factors signal retrogradely in lesioned peripheral nerve.
Retrograde axonal injury signalling stimulates cell body responses in lesioned peripheral neurons. The involvement of importins in retrograde transport suggests that transcription factors (TFs) might be directly involved in axonal injury signalling. Here, we show that multiple TFs are found in axons and associate with dynein in axoplasm from injured nerve. Biochemical and functional validation ...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2012
ISSN: 0261-4189
DOI: 10.1038/emboj.2011.494